Dr Wandiahyel Yaduma

Dr Wandiahyel Yaduma have experience teaching Biomedical sciences for undergraduate and postgraduate students. He has experience as a Module Leader delivering range of learning, teaching, assessment, and feedback activities. He has contributed to the designing and developing of appropriate teaching material related Biomedical Sciences. He is also comfortable teaching within Life Sciences courses at undergraduate and postgraduate levels and supervising final-year projects students. He has great understand working in a Life Science specific discipline and have engaged and provided pastoral care to students within the subject area.

Dr Wandiahyel Yaduma’s research interests focus on the regulation of cell division cycle using the fission yeast Schizosaccharomyces pombe as a model organism. Cytokinesis is the final step of the cell division cycle, and the major events of the process are conserved from fungi to animal cells when cellular constituents are separated to produce two daughter cells. Cytokinesis by the fission yeast S. pombe is compromised by the loss of anillin/Mid1p and they assemble slowly into an abnormal contractile ring. Phosphorylation by aurora and polo kinase during different cell cycle steps regulates several aspects of Mid1p function. Hence, my research interest is focussed on understanding the genetic interactions between the mid1 and vps4 genes, the physical interactions between Mid1p and Vps4p proteins, and the mechanisms by which they work together to regulate one another during cytokinesis.

List of publications:

Yaduma, G. Y., Rezig, I. M., Gwyn, W. G., & Christopher, J. M. (2024). Phosphorylation of anillin/Mid1p in fission yeast regulates it sub-cellular distribution and is required for cytokinesis, accepted by Cell Cycle.

Rezig, I. M., Yaduma, G. Y., & Christopher, J. M. (2024). Processes Controlling the Contractile Ring During Cytokinesis in Fission Yeast Including the Role of ESCRT Proteins. Journal of Fungal, 10(2), 154. https://doi:10.3390/jof10020154

Rezig, I. M., Yaduma, G. Y., Gwyn, W. G., & Christopher, J. M. (2022). The Role of Anillin/Mid1p during medial division and cytokinesis: From Fission Yeast to Cancer Cells, Cell Cycle, https://doi.org/10.1080/15384101.2022.217655

Rezig, I. M., Yaduma, G. Y., Gwyn, W. G., & Christopher J. M. (2021). Anillin/Mid1p Interacts with the ESCRT- Associate Protein Vps4 and Mitotic Kinases to Regulate Cytokinesis in Fission Yeast, Cell Cycle, https://doi.org/10.1080/15384101.2021.1962637

Williams, K. J., and Yaduma, G. Y. (2021). The Use of Bacillus subtilis Bacteria as a Tool to Assess the Toxicity of Pharmaceuticals in the Environment, African Journal of Biological Sciences, https://doi.org/10.33472/AFJBS.3.2.2021.42-49

Emmanuel, N. S, Yaduma, G. Y., Kashini A, Husainy, A.Y., Malgwi, I. S. & Momoh, I. J. (2020). Changes in Liver Oxidative Stress Biomarkers, Biochemicals and Histological Assessment in Lactating Wistar Rats Following Oral Monosodium Glutamate (MSG) Administration. EC Pharmacology and Toxicology 8.11 (2020): 14-25.

Wandiahyel, G, Y., Nachamada, E. S., Neftiya, Y., Ibrahim, M. S. & Dluya T. (2020). Preliminary Evaluation of Hepatorenal Protective Potentials of Kigelia afriacana Ethanolic Leaf Extract on Carbon Tetrachloride Induced Toxicity in Adult Male Wister Rats. American Journal of Plant Science, https://doi.org/10.4236/ajps.2020.119096

Yaduma, G. W., Hickson S., Thagriki, D. S. & Emmanuel, N. S. (2018). Medicinal Potential of Kigelia africana Leaf Fractions on Rats Induced CCl4 Toxicity. Chemistry research Journal 3(3): 123-129.

Member Biochemical Society
Member Microbiology Society and British Yeast Group
Associate Fellow HEA